MOPAN produces topical studies to inform members on emerging issues in the multilateral system. In 2021, MOPAN launched a new series of studies entitled, Lessons in Multilateral Effectiveness. These studies are learning-focused, and aim to contribute to strengthening the multilateral system by informing policy discussions.

As with assessments, MOPAN studies are undertaken in collaboration with multilateral organisations. The Secretariat oversees the preparation of the studies, and reference groups composed of experts from member countries provide strategic guidance to the studies.